PHF1 antibody (N-Term)

Catalog No. ABIN2781208

The Rabbit Polyclonal anti-PHF1 antibody has been validated for WB. It is suitable to detect PHF1 in samples from Human, Rat, Dog, Rabbit, Cow, Guinea Pig and Horse.

Quick Overview for PHF1 antibody (N-Term) (ABIN2781208)

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Reactivity: Human, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHF1 Antibody

Binding Specificity: N-Term

Sequence: MAQPPRLSRS GASSLWDPAS PAPTSGPRPR LWEGQDVLAR WTDGLLYLGT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PHF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 567 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHF1

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Alternative Name: PHF1

Background: PHF1 has significant sequence similarity with Drosophila Polycomblike. It contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.
Alias Symbols: PHF2, PCL1, MTF2L2
Protein Interaction Partner: ATXN7L1, BIRC7, VAC14, HSD17B14, RBPMS, CALCOCO2, PDLIM7, TFCP2, NAB2, TRIM23, SUZ12, EZH2, NEK6, TP53, SUMO1, HIC1, ELAVL1, UBC, RAD50, NCR1, EED, SMC1A, XRCC5, RBBP7, XRCC6, DHX9, HIST1H3J, HIST1H3G, HIST1H3I, HIST1H3E, HIST1H3C, HIST1H3A, HIST1H3F, HIS
Protein Size: 567

Molecular Weight: 62 kDa

Gene ID: 5252

NCBI Accession: NM_024165, NP_077084

UniProt: O43189