NSMCE1 antibody (N-Term)

Catalog No. ABIN2781253

This anti-NSMCE1 antibody is a Rabbit Polyclonal antibody detecting NSMCE1 in WB. Suitable for Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Goat, Dog, Horse and Zebrafish (Danio rerio).

Quick Overview for NSMCE1 antibody (N-Term) (ABIN2781253)

Target: NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Goat, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSMCE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NSMCE1 Antibody

Binding Specificity: N-Term

Sequence: RPIYALVNLA TTSISKMATD FAENELDLFR KALELIIDSE TGFASSTNIL

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against NSMCE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NSMCE1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 256 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NSMCE1

Target: NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Alternative Name: NSMCE1

Background: NSMCE1 is a probable component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
Alias Symbols: NSE1
Protein Interaction Partner: UBC, EID3, SMC6, NDNL2, Ube2k, UBE2D2, NSMCE2, NSMCE1, NSMCE4A, SMC5, SUMO2, MAGEF1,
Protein Size: 256

Molecular Weight: 28 kDa

Gene ID: 197370

NCBI Accession: NM_145080, NP_659547

UniProt: Q8WV22

Pathways: Positive Regulation of Response to DNA Damage Stimulus