ABCD4 antibody (C-Term)

Catalog No. ABIN2781509

The Rabbit Polyclonal anti-ABCD4 antibody has been validated for WB. It is suitable to detect ABCD4 in samples from Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow, Horse and Saccharomyces cerevisiae.

Quick Overview for ABCD4 antibody (C-Term) (ABIN2781509)

Target: ABCD4 (ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCD4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ABCD4 Antibody

Binding Specificity: C-Term

Sequence: FGPHGVLFLP QKPFFTDGTL REQVIYPLKE VYPDSGSADD ERILRFLELA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%

Characteristics: This is a rabbit polyclonal antibody against ABCD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ABCD4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 497 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABCD4

Target: ABCD4 (ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4))

Alternative Name: ABCD4

Background: ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.
Alias Symbols: ABC41, EST352188, P70R, P79R, PMP69, PXMP1L
Protein Interaction Partner: UBC, SARAF, PEA15, XRCC6, DLEU1,
Protein Size: 497

Molecular Weight: 55 kDa

Gene ID: 5826

NCBI Accession: NM_005050

UniProt: O14678