SLC7A1 antibody (N-Term)

Catalog No. ABIN2781583

The Rabbit Polyclonal anti-SLC7A1 antibody has been validated for WB. It is suitable to detect SLC7A1 in samples from Human, Cow, Horse, Rabbit and Pig. There is 1 publication available.

Quick Overview for SLC7A1 antibody (N-Term) (ABIN2781583)

Target: SLC7A1 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1))

Reactivity: Human, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC7A1 Antibody

Binding Specificity: N-Term

Sequence: LGFIMVSGFV KGSVKNWQLT EEDFGNTSGR LCLNNDTKEG KPGVGGFMPF

Predicted Reactivity: Cow: 100%, Horse: 93%, Human: 100%, Pig: 86%, Rabbit: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC7A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC7A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 629 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC7A1 antibody (ABIN2781583)

Kaneko, Okuda-Ashitaka, Ando, Nishimura, Igarashi, Maeda, Furuta, Suzuki, Matsumura, Ito: "Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells." in: American journal of physiology. Cell physiology, Vol. 293, Issue 2, pp. C729-37, (2007) (PubMed).

Target Details for SLC7A1

Target: SLC7A1 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1))

Alternative Name: SLC7A1

Background: SLC7A1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It may also function as an ecotropic retroviral leukemia receptor.
Alias Symbols: ATRC1, CAT-1, ERR, HCAT1, REC1L
Protein Interaction Partner: FATE1, UBC, BAG3, APP, ELAVL1,
Protein Size: 629

Molecular Weight: 68 kDa

Gene ID: 6541

NCBI Accession: NM_003045, NP_003036

UniProt: P30825

Pathways: Dicarboxylic Acid Transport