FUT1 antibody (Middle Region)

Catalog No. ABIN2781768

The Rabbit Polyclonal anti-FUT1 antibody has been validated for WB. It is suitable to detect FUT1 in samples from Human, Mouse, Rat, Dog, Goat, Horse, Rabbit, Cow and Guinea Pig. There is 1 publication available.

Quick Overview for FUT1 antibody (Middle Region) (ABIN2781768)

Target: FUT1 (Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1))

Reactivity: Human, Mouse, Rat, Dog, Goat, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FUT1 Antibody

Binding Specificity: Middle Region

Sequence: EATPWKDFAL LTQCNHTIMT IGTFGFWAAY LAGGDTVYLA NFTLPDSEFL

Predicted Reactivity: Cow: 92%, Dog: 100%, Goat: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FUT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FUT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 365 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FUT1 antibody (ABIN2781768)

Kondoh, Tateno, Hirabayashi, Yasumoto, Nakao, Oishi: "Molecular clock regulates daily ?1-2-fucosylation of NCAM within mouse secondary olfactory neurons." in: The Journal of biological chemistry, (2014) (PubMed).

Target Details for FUT1

Target: FUT1 (Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1))

Alternative Name: FUT1

Background: The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.
Alias Symbols: H, HH, HSC
Protein Interaction Partner: CEBPA,
Protein Size: 365

Molecular Weight: 41 kDa

Gene ID: 2523

NCBI Accession: NM_000148, NP_000139

UniProt: P19526