SGCB antibody (Middle Region)

Catalog No. ABIN2781778

The Rabbit Polyclonal anti-SGCB antibody is suitable to detect SGCB in samples from Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for SGCB antibody (Middle Region) (ABIN2781778)

Target: SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGCB Antibody

Binding Specificity: Middle Region

Sequence: RIGPNGCDSM ELHESGLLRF KQVSDMGVIH PLYKSTVGGR RNENLVITGN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SGCB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SGCB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGCB

Target: SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))

Alternative Name: SGCB

Background: This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
Alias Symbols: A3b, SGC, LGMD2E
Protein Size: 318

Molecular Weight: 34 kDa

Gene ID: 6443

NCBI Accession: NM_000232, NP_000223

UniProt: Q16585

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location