AQP2 antibody (Middle Region)

Catalog No. ABIN2781806

This Rabbit Polyclonal antibody specifically detects AQP2 in WB and IF. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Sheep, Guinea Pig and Horse.

Quick Overview for AQP2 antibody (Middle Region) (ABIN2781806)

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Sheep, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-AQP2 Antibody

Binding Specificity: Middle Region

Sequence: ALSIGFSVTL GHLLGIYFTG CSMNPARSLA PAVVTGKFDD HWVFWIGPLV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against Aqp2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 271 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AQP2

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Alternative Name: Aqp2

Background: Aqp2 forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Alias Symbols: AQP-CD, WCH-CD, cph, jpk
Protein Interaction Partner: Vamp3, Vamp2,
Protein Size: 271

Molecular Weight: 29 kDa

Gene ID: 11827

NCBI Accession: NM_009699, NP_033829

UniProt: P56402

Pathways: Response to Water Deprivation