AWAT2 antibody (C-Term)
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- Target See all AWAT2 products
- AWAT2 (Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AWAT2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GEPLPMPKIE NPSQEIVAKY HTLYIDALRK LFDQHKTKFG ISETQELEII
- Predicted Reactivity
- Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against DGAT2L4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human DGAT2L4
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 333 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- AWAT2 (Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2))
- Alternative Name
- DGAT2L4 (AWAT2 Products)
- Synonyms
- DGAT2L4 antibody, ARAT antibody, DC4 antibody, MFAT antibody, WS antibody, 9430062J17Rik antibody, Dgat2l4 antibody, RGD1565111 antibody, acyl-CoA wax alcohol acyltransferase 2 antibody, AWAT2 antibody, Awat2 antibody
- Background
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DGAT2L4 is acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. It has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. DGAT2L4 may also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters, however this activity is unclear in vivo.
Alias Symbols: AWAT2, DC4, MFAT, WS, DGAT2L4
Protein Size: 333 - Molecular Weight
- 38 kDa
- Gene ID
- 158835
- NCBI Accession
- NM_001002254, NP_001002254
- UniProt
- Q6E213
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