FMO3 antibody (N-Term)

Catalog No. ABIN2781862

The Rabbit Polyclonal anti-FMO3 antibody has been validated for WB and IHC. It is suitable to detect FMO3 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit and Pig. There is 1 publication available.

Quick Overview for FMO3 antibody (N-Term) (ABIN2781862)

Target: FMO3 (Flavin Containing Monooxygenase 3 (FMO3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMO3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FMO3 Antibody

Binding Specificity: N-Term

Sequence: FMHNSKIQEY IIAFAKEKNL LKYIQFKTFV SSVNKHPDFA TTGQWDVTTE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 90%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FMO3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FMO3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 532 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FMO3 antibody (ABIN2781862)

Ganti, Skapek, Zhang, Fuller, Wu, Billups, Breitfeld, Dalton, Meyer, Khoury: "Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 19, Issue 9, pp. 1213-20, (2006) (PubMed).

Target Details for FMO3

Target: FMO3 (Flavin Containing Monooxygenase 3 (FMO3))

Alternative Name: FMO3

Background: FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It acts on TMA to produce TMA-N-oxide.
Alias Symbols: FMOII, MGC34400, dJ127D3.1, TMAU
Protein Size: 532

Molecular Weight: 59 kDa

Gene ID: 2328

NCBI Accession: NM_001002294, NP_001002294

UniProt: P31513