FURIN antibody (N-Term)

Catalog No. ABIN2782180

This Rabbit Polyclonal antibody specifically detects FURIN in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Sheep, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for FURIN antibody (N-Term) (ABIN2782180)

Target: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Reactivity: Human, Mouse, Rat, Cow, Sheep, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FURIN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FURIN Antibody

Binding Specificity: N-Term

Sequence: RDVYQEPTDP KFPQQWYLSG VTQRDLNVKA AWAQGYTGHG IVVSILDDGI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FURIN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FURIN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 794 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FURIN

Target: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Alternative Name: FURIN

Background: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a c
Alias Symbols: FUR, PACE, PCSK3, SPC1
Protein Interaction Partner: env, UBC, ABCC6, ELAVL1, ZP4, ITM2C, COL23A1, NAGPA, SORCS1, BACE1, PACS1, ADAMTS1, LECT1, TNFSF13, ADAMTS4, ADAM19, SORL1, SERPINB8, AP2M1, EDA, FLNA, VWF, NOTCH1, ZP3, PRB4, PMCH, PDGFA, DSG3, FURIN, LRP1, FLNC,
Protein Size: 794

Molecular Weight: 74 kDa

Gene ID: 5045

NCBI Accession: NM_002569, NP_002560

UniProt: P09958

Pathways: Notch Signaling, Neurotrophin Signaling Pathway