Protocadherin 1 antibody (N-Term)

Catalog No. ABIN2782181

The Rabbit Polyclonal anti-Protocadherin 1 antibody has been validated for WB and ICC. It is suitable to detect Protocadherin 1 in samples from Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig, Pig and Zebrafish (Danio rerio).

Quick Overview for Protocadherin 1 antibody (N-Term) (ABIN2782181)

Target: Protocadherin 1 (PCDH1)

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Protocadherin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-Protocadherin 1 Antibody

Binding Specificity: N-Term

Sequence: LLPSMLLALL LLLAPSPGHA TRVVYKVPEE QPPNTLIGSL AADYGFPDVG

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PCDH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1060 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Protocadherin 1

Target: Protocadherin 1 (PCDH1)

Alternative Name: PCDH1

Background: PCDH1 belongs to the protocadherin subfamily within the cadherin superfamily. It is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity.This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Alias Symbols: MGC45991, PC42, PCDH42
Protein Interaction Partner: UBC, SMAD3, ALB, VKORC1, ATF7IP,
Protein Size: 1060

Molecular Weight: 111 kDa

Gene ID: 5097

NCBI Accession: NM_002587, NP_002578

UniProt: Q08174