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Protocadherin gamma Subfamily C, 3 (PCDHGC3) (N-Term) antibody

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB. Suitable for Human, Rat, Mouse, Guinea Pig, Horse, Cow, Dog and Zebrafish (Danio rerio).
Catalog No. ABIN2782182

Quick Overview for Protocadherin gamma Subfamily C, 3 (PCDHGC3) (N-Term) antibody (ABIN2782182)

Target

See all Protocadherin gamma Subfamily C, 3 (PCDHGC3) Antibodies
Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Reactivity

  • 50
  • 12
  • 11
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Rat, Mouse, Guinea Pig, Horse, Cow, Dog, Zebrafish (Danio rerio)

Host

  • 46
  • 4
Rabbit

Clonality

  • 47
  • 3
Polyclonal

Conjugate

  • 19
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Un-conjugated

Application

  • 40
  • 24
  • 13
  • 13
  • 11
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 15
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequence

    ISEAVAPGTR FPLESAHDPD VGSNSLQTYE LSRNEYFALR VQTREDSTKY

    Predicted Reactivity

    Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

    Characteristics

    This is a rabbit polyclonal antibody against PCDHGC3. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHGC3
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 863 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    Protocadherin gamma Subfamily C, 3 (PCDHGC3)

    Alternative Name

    PCDHGC3

    Background

    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. PCDHGC3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    Alias Symbols: PC43, PCDH-GAMMA-C3, PCDH2
    Protein Interaction Partner: UBC, MFSD3, HGD, APP,
    Protein Size: 863

    Molecular Weight

    91 kDa

    Gene ID

    5098

    NCBI Accession

    NM_032402, NP_115778
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