SSR1 antibody (N-Term)

Catalog No. ABIN2782211

This anti-SSR1 antibody is a Rabbit Polyclonal antibody detecting SSR1 in WB and IHC. Suitable for Human, Mouse, Dog, Rat, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Pig and Saccharomyces cerevisiae.

Quick Overview for SSR1 antibody (N-Term) (ABIN2782211)

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Reactivity: Human, Mouse, Dog, Rat, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SSR1 Antibody

Binding Specificity: N-Term

Sequence: DDEAEVEEDE PTDLVEDKEE EDVSGEPEAS PSADTTILFV KGEDFPANNI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SSR1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SSR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 286 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSR1

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Alternative Name: SSR1

Background: The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein.The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.
Alias Symbols: DKFZp781N23103, TRAPA
Protein Interaction Partner: HUWE1, ILK, EDEM1, SERPINF2, SERPINA1, ODC1, MYC, HSPA5, MDC1, SFXN1, HM13, ACAD9, FKBP8, CCT5, CCT2, CCT4, TCP1, SRSF1, PSAP, HNRNPM, ILF3, FLOT2, ABCC2, ATP6V1C1, FBXO6, CAND1, CUL3, ELAVL1, HDGF, UBC, SUMO2, HSPA13, UTP14A, NUP54, DKC1, PTN, EEF1A1,
Protein Size: 286

Molecular Weight: 32 kDa

Gene ID: 6745

NCBI Accession: NM_003144, NP_003135

UniProt: P43307

Pathways: ER-Nucleus Signaling