CPS1 antibody (N-Term)

Catalog No. ABIN2782318

This anti-CPS1 antibody is a Rabbit Polyclonal antibody detecting CPS1 in WB and IHC. Suitable for Human, Rat, Mouse, Dog, Guinea Pig, Cow, Rabbit and Pig.

Quick Overview for CPS1 antibody (N-Term) (ABIN2782318)

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Cow, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CPS1 Antibody

Binding Specificity: N-Term

Sequence: QWLQEEKVPA IYGVDTRMLT KIIRDKGTML GKIEFEGQPV DFVDPNKQNL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CPS1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CPS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1500 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CPS1

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Alternative Name: CPS1

Background: Carbamoyl phosphate synthetase I is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis.Carbamoyl phosphate synthetase I (EC 6.3.4.16) is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis (CAD, MIM 114010), which has been mapped to 2p21.[supplied by OMIM].
Alias Symbols: CPSASE1
Protein Interaction Partner: AGO2, ASB1, FBXO6, UBC, MRPS26, LRPPRC, TOMM70A, SEC22B, PCBP1, HSPA9, HSPA1A, FH, CPT1A, MYC, ELAVL1, SUMO2, RAD21, Csnk1e, Cdk1, RICTOR, YWHAQ, H2AFX, ARAF, RAF1,
Protein Size: 1500

Molecular Weight: 165 kDa

Gene ID: 1373

NCBI Accession: NM_001875, NP_001866

UniProt: P31327

Pathways: Response to Growth Hormone Stimulus, Cellular Glucan Metabolic Process