UBASH3A antibody (Middle Region)

Catalog No. ABIN2782357

The Rabbit Polyclonal anti-UBASH3A antibody (ABIN2782357) specifically detects UBASH3A in WB. The antibody is reactive with Human, Mouse, Rat, Horse, Cow, Rabbit, Pig and Saccharomyces cerevisiae samples.

Quick Overview for UBASH3A antibody (Middle Region) (ABIN2782357)

Target: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Reactivity: Human, Mouse, Rat, Horse, Cow, Rabbit, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBASH3A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBASH3A Antibody

Binding Specificity: Middle Region

Sequence: PCSLPRRSRG IKDFENDPPL SSCGIFQSRI AGDALLDSGI RISSVFASPA

Predicted Reactivity: Cow: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 79%, Rat: 93%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against UBASH3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBASH3A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 661 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBASH3A

Target: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Alternative Name: UBASH3A

Background: UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. It also promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
Alias Symbols: CLIP4, STS-2, TULA, TULA-1
Protein Interaction Partner: KRT40, SF3B4, SPRY2, DAZAP2, TP53BP2, REL, TRIM37, KCNE1, CBS, UBC, CRK, UBASH3B, PARK2, CBL, ABCE1, gag, AIFM1, EGFR, ALK, DNM1, UBB, UBE2L3,
Protein Size: 661

Molecular Weight: 74 kDa

Gene ID: 53347

NCBI Accession: NM_018961, NP_061834

UniProt: P57075