USP16 antibody (N-Term)

Catalog No. ABIN2782358

This Rabbit Polyclonal antibody specifically detects USP16 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig and Horse.

Quick Overview for USP16 antibody (N-Term) (ABIN2782358)

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP16 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-USP16 Antibody

Binding Specificity: N-Term

Sequence: CKTDNKVKDK AEEETEEKPS VWLCLKCGHQ GCGRNSQEQH ALKHYLTPRS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 92%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against USP16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human USP16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 408 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP16

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Alternative Name: USP16

Background: USP16 is a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division.
Alias Symbols: UBP-M
Protein Interaction Partner: RNF8, HERC2, USP16, HIST1H2AB, XPO1, HIST1H2BB, CDK1, HIST2H2AC, HIST2H2AA3, UBC, IGF2BP3, TXNL1, CSNK1D, HIST4H4, FBXO11, PTOV1, UBD, hist1h3g, CALM1, HIST1H2BL, DBT, EXOSC10,
Protein Size: 408

Molecular Weight: 44 kDa

Gene ID: 10600

NCBI Accession: NM_001001992

UniProt: Q5VKN8