MRPS6 antibody (C-Term)

Catalog No. ABIN2782399

The Rabbit Polyclonal anti-MRPS6 antibody has been validated for WB. It is suitable to detect MRPS6 in samples from Human.

Quick Overview for MRPS6 antibody (C-Term) (ABIN2782399)

Target: MRPS6 (Mitochondrial Ribosomal Protein S6 (MRPS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPS6 Antibody

Binding Specificity: C-Term

Sequence: ESMVEHLSRD IDVIRGNIVK HPLTQELKEC EGIVPVPLAE KLYSTKKRKK

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MRPS6. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MRPS6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 125 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPS6

Target: MRPS6 (Mitochondrial Ribosomal Protein S6 (MRPS6))

Alternative Name: MRPS6

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q.
Alias Symbols: S6mt, RPMS6, MRP-S6, C21orf101
Protein Interaction Partner: MKRN3, SRPK2, ICT1, RNF181, STAT5A, SREBF2, APP, SRRM2, LRIF1, KIAA1377,
Protein Size: 125

Molecular Weight: 14 kDa

Gene ID: 64968

NCBI Accession: NM_032476, NP_115865

UniProt: P82932