Adenylate Kinase 2 antibody (N-Term)

Catalog No. ABIN2782460

This Rabbit Polyclonal antibody specifically detects Adenylate Kinase 2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Horse, Cow and Dog.

Quick Overview for Adenylate Kinase 2 antibody (N-Term) (ABIN2782460)

Target: Adenylate Kinase 2 (AK2)

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Horse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenylate Kinase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Adenylate Kinase 2 Antibody

Binding Specificity: N-Term

Sequence: MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against AK2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AK2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 239 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adenylate Kinase 2

Target: Adenylate Kinase 2 (AK2)

Alternative Name: AK2

Background: Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates, this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: ADK2, AK 2
Protein Interaction Partner: HUWE1, UBC, MDM2, BAG3, ABCC5, ABCC6, TUFM, SAFB, MRPL12, IDH1, DSP, DLD, RAVER1, TELO2, CUL3, SHBG, SUMO2, MEPCE,
Protein Size: 239

Molecular Weight: 26 kDa

Gene ID: 204

NCBI Accession: NM_001625, NP_001616

UniProt: P54819

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process