ATIC antibody (N-Term)

Catalog No. ABIN2782481

The Rabbit Polyclonal anti-ATIC antibody (ABIN2782481) specifically detects ATIC in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Guinea Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio) samples.

Quick Overview for ATIC antibody (N-Term) (ABIN2782481)

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATIC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATIC Antibody

Binding Specificity: N-Term

Sequence: YVVVSTEMQS SESKDTSLET RRQLALKAFT HTAQYDEAIS DYFRKQYSKG

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ATIC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATIC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 592 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATIC

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Alternative Name: ATIC

Background: ATIC is a bifunctional protein requiring dimerization for transformylase activity.
Alias Symbols: AICAR, AICARFT, IMPCHASE, PURH
Protein Interaction Partner: UBC, NEDD8, SUMO1, ASB6, TATDN1, NSFL1C, OGFOD1, STK26, ISOC1, MCTS1, PROSC, PAPSS1, NAE1, YWHAE, UBA1, PTMA, PAFAH1B1, MYO1E, MSN, IPO5, FH, CTH, CAPN2, AHCY, GMDS, TARDBP, TYMS, TXN, SUMO2, RBBP6, OXCT1, CRK, CLNS1A, CDK2, ISG15, SIRT7, EGFR, ATIC, CMBL
Protein Size: 592

Molecular Weight: 64 kDa

Gene ID: 471

NCBI Accession: NM_004044, NP_004035

UniProt: P31939