UBD antibody (N-Term)

Catalog No. ABIN2782518

This Rabbit Polyclonal antibody specifically detects UBD in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Rabbit and Pig.

Quick Overview for UBD antibody (N-Term) (ABIN2782518)

Target: UBD (Ubiquitin D (UBD))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBD Antibody

Binding Specificity: N-Term

Sequence: RSKTKVPVQD QVLLLGSKIL KPRRSLSSYG IDKEKTIHLT LKVVKPSDEE

Predicted Reactivity: Cow: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against UBD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 165 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBD

Target: UBD (Ubiquitin D (UBD))

Alternative Name: UBD

Background: UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is not significantly overexpressed in cancers lacking a proinflammatory environment. Immunohistochemical studies demonstrated increased UBD expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.
Alias Symbols: FAT10, UBD-3, GABBR1
Protein Interaction Partner: UBE2Z, SRPK2, SRPK1, RPLP0, RPL27A, RPL23A, RPL12, RPL11, SNORA62, RBBP4, RANBP2, QARS, PSMD2, PRKDC, PRKCSH, PPIB, PPIA, PLEC, PGK1, PCNA, PCBP1, P4HB, NSUN2, TRIM28, PDIA6, ABCF2, SMC4, PDCD6IP, NPEPPS, EFTUD2, PAPSS2, HIP1R, SNORD73A, IQGAP1, PABPC4, E
Protein Size: 165

Molecular Weight: 18 kDa

Gene ID: 10537

NCBI Accession: NM_006398, NP_006389

UniProt: O15205

Pathways: Ubiquitin Proteasome Pathway