WBP11 antibody (N-Term)

Catalog No. ABIN2782558

This Rabbit Polyclonal antibody specifically detects WBP11 in WB, IP and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) and Cow.

Quick Overview for WBP11 antibody (N-Term) (ABIN2782558)

Target: WBP11 (WW Domain Binding Protein 11 (WBP11))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WBP11 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Product Details anti-WBP11 Antibody

Binding Specificity: N-Term

Sequence: GRRSTSSTKS GKFMNPTDQA RKEARKRELK KNKKQRMMVR AAVLKMKDPK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against WBP11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WBP11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 641 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WBP11

Target: WBP11 (WW Domain Binding Protein 11 (WBP11))

Alternative Name: WBP11

Background: WBP11 is a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. WBP11has 95 % amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95 % amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
Alias Symbols: DKFZp779M1063, NPWBP, SIPP1, WBP-11
Protein Interaction Partner: TESC, TRAF4, GRB2, FYN, UBC, BMI1, APBB1, WBP4, HECW2, DDX17, RBM5, PPP1CA, DDX5, CTNNBL1, PPP1CC, UPF3B, ZC3H13, CPSF6, SNRPB2, PQBP1, CD2BP2, SF3A2, ITSN1, RTN4IP1, PPP1CB, GIGYF2, MCRS1, PRPF40A, C5orf22, NCK2, TRIP10, NCF1, VIM, SRC, PIK3R1, RUNX1T1,
Protein Size: 641

Molecular Weight: 70 kDa

Gene ID: 51729

NCBI Accession: NM_016312, NP_057396

UniProt: Q9Y2W2