TMEM48 antibody (Middle Region)

Catalog No. ABIN2782564

This anti-TMEM48 antibody is a Rabbit Polyclonal antibody detecting TMEM48 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio) and Pig.

Quick Overview for TMEM48 antibody (Middle Region) (ABIN2782564)

Target: TMEM48 (Transmembrane Protein 48 (TMEM48))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM48 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMEM48 Antibody

Binding Specificity: Middle Region

Sequence: SFTEDRFGVV QTTLPAILNT LLTLQEAVDK YFKLPHASSK PPRISGSLVD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against TMEM48. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM48

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 674 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMEM48

Target: TMEM48 (Transmembrane Protein 48 (TMEM48))

Alternative Name: TMEM48

Background: TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
Alias Symbols: FLJ10407, FLJ12556, FLJ34120, NDC1, RP4-654H19.1, NET3, TMEM48
Protein Interaction Partner: UBC, Ndc1, NUP93,
Protein Size: 674

Molecular Weight: 76 kDa

Gene ID: 55706

NCBI Accession: NM_018087, NP_060557

UniProt: Q9BTX1