TSR1 antibody (Middle Region)

Catalog No. ABIN2782565

This Rabbit Polyclonal antibody specifically detects TSR1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for TSR1 antibody (Middle Region) (ABIN2782565)

Target: TSR1 (TSR1, 20S rRNA Accumulation, Homolog (TSR1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TSR1 Antibody

Binding Specificity: Middle Region

Sequence: MALVATVYAP ITFPPASVLL FKQKSNGMHS LIATGHLMSV DPDRMVIKRV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against TSR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 804 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TSR1 antibody (ABIN2782565)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for TSR1

Target: TSR1 (TSR1, 20S rRNA Accumulation, Homolog (TSR1))

Alternative Name: TSR1

Background: TSR1 belongs to the BMS1/TSR1 family and TSR1 subfamily. TSR1 is required during maturation of the 40S ribosomal subunit in the nucleolus.
Alias Symbols: FLJ10534, KIAA1401, MGC131829
Protein Interaction Partner: UBC, TARBP2, FTSJ3, LIN28A, RPA3, RPA2, RPA1, WIBG, WDR26, PNO1, SERBP1, KIAA0368, RANBP9, RPS29, RPS28, RPS27, RPS26, RPS25, RPS24, RPS23, RPS20, RPS19, RPS18, RPS16, RPS15A, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS6, RPS5, RPS4X, RPS3A, RPS3, R
Protein Size: 804

Molecular Weight: 92 kDa

Gene ID: 55720

NCBI Accession: NM_018128, NP_060598

UniProt: Q2NL82

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly