ADAM9 antibody (Middle Region)

Catalog No. ABIN2782602

Product Details anti-ADAM9 Antibody

Target: ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM9 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NKGGNCLLNI PKPDEAYSAP SCGNKLVDAG EECDCGTPKE CELDPCCEGS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against ADAM9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADAM9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 655 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADAM9

Target: ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))

Alternative Name: ADAM9 (ADAM9 Products)

Background: ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM9 interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms.
Alias Symbols: KIAA0021, MCMP, MDC9, Mltng, CORD9
Protein Interaction Partner: UBC, RNF2, CDH1, SH3D19, SH3GLB1, SNX9, MAD2L2, ITGA3, ITGAV, TNF, PRKCD, ITGA6, SH3GL2,
Protein Size: 655

Molecular Weight: 69 kDa

Gene ID: 8754

NCBI Accession: NM_001005845, NP_001005845

UniProt: B7ZLN7

Pathways: Cellular Response to Molecule of Bacterial Origin, SARS-CoV-2 Protein Interactome