COX6A1 antibody (N-Term)

Catalog No. ABIN2782631

The Rabbit Polyclonal anti-COX6A1 antibody has been validated for WB. It is suitable to detect COX6A1 in samples from Human.

Quick Overview for COX6A1 antibody (N-Term) (ABIN2782631)

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COX6A1 Antibody

Binding Specificity: N-Term

Sequence: VVGVSSVSRL LGRSRPQLGR PMSSGAHGEE GSARMWKTLT FFVALPGVAV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against COX6A1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 109 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COX6A1

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Alternative Name: COX6A1

Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66 % amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.
Alias Symbols: COX6A, COX6AL, MGC104500
Protein Interaction Partner: Htt, UBC, GRB2,
Protein Size: 109

Molecular Weight: 10 kDa

Gene ID: 1337

NCBI Accession: NM_004373, NP_004364

UniProt: P12074