Corin antibody (C-Term)

Catalog No. ABIN2782723

The Rabbit Polyclonal anti-Corin antibody is suitable to detect Corin in samples from Human, Mouse, Rat, Cow, Horse, Guinea Pig, Rabbit and Pig. It has been validated for WB.

Quick Overview for Corin antibody (C-Term) (ABIN2782723)

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Reactivity: Human, Mouse, Rat, Cow, Horse, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Corin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Corin Antibody

Binding Specificity: C-Term

Sequence: HPRYSRAVVD YDISIVELSE DISETGYVRP VCLPNPEQWL EPDTYCYITG

Predicted Reactivity: Cow: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CORIN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CORIN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 685 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Alternative Name: CORIN

Background: CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
Alias Symbols: ATC2, CRN, Lrp4, MGC119742, TMPRSS10
Protein Size: 685

Molecular Weight: 74 kDa

Gene ID: 10699

NCBI Accession: NM_006587

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones