Corin antibody (C-Term)

Catalog No. ABIN2782723

Product Details anti-Corin Antibody

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Horse, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Corin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HPRYSRAVVD YDISIVELSE DISETGYVRP VCLPNPEQWL EPDTYCYITG

Predicted Reactivity: Cow: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CORIN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CORIN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 685 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Alternative Name: CORIN (CORIN Products)

Background: CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
Alias Symbols: ATC2, CRN, Lrp4, MGC119742, TMPRSS10
Protein Size: 685

Molecular Weight: 74 kDa

Gene ID: 10699

NCBI Accession: NM_006587

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones