ATP1B4 antibody (Middle Region)

Catalog No. ABIN2782764

The Rabbit Polyclonal anti-ATP1B4 antibody (ABIN2782764) specifically detects ATP1B4 in WB. The antibody is reactive with Rat, Human, Cow, Dog, Guinea Pig, Horse, Mouse and Rabbit samples.

Quick Overview for ATP1B4 antibody (Middle Region) (ABIN2782764)

Target: ATP1B4 (ATPase, Na+/K+ Transporting, beta 4 Polypeptide (ATP1B4))

Reactivity: Rat, Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1B4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP1B4 Antibody

Binding Specificity: Middle Region

Sequence: ACQFKRSFLK NCSGLEDPTF GYSTGQPCIL LKMNRIVGFR PELGDPVKVS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ATP1B4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATP1B4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 353 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP1B4

Target: ATP1B4 (ATPase, Na+/K+ Transporting, beta 4 Polypeptide (ATP1B4))

Alternative Name: ATP1B4

Background: This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: -
Protein Size: 353

Molecular Weight: 41 kDa

Gene ID: 23439

NCBI Accession: NM_012069, NP_036201

UniProt: Q9UN42

Pathways: Thyroid Hormone Synthesis, Proton Transport