DNAJB11 antibody (C-Term)
Quick Overview for DNAJB11 antibody (C-Term) (ABIN2782885)
Target
See all DNAJB11 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- FDNNNIKGSL IITFDVDFPK EQLTEEAREG IKQLLKQGSV QKVYNGLQGY
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
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Characteristics
- This is a rabbit polyclonal antibody against DNAJB11. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human DNAJB11
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 358 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))
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Alternative Name
- DNAJB11
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Background
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DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a C-terminal cysteine-rich region.DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1723 BC046500.1 710-2432
Alias Symbols: ABBP-2, ABBP2, EDJ, ERdj3, ERj3, HEDJ, PRO1080, UNQ537, hDj9, DJ9, Dj-9, ERj3p, hDj-9
Protein Interaction Partner: PCSK9, GPX7, VCP, AGO1, SMOC1, CORO1C, FBXO6, ADRB2, HDAC11, MMS19, METTL23, env, UBC, MYC, IKBKAP, OS9, PAXIP1, ESR1, ECH1, DNASE2, ANXA4, ACP2, NADK2, UBXN1, RRM1, PNP, NDUFV1, MAN2B1, EPHX1, CUL3, ELAVL1, SUMO4, SIMC1, UBR1, SPRED1, CEP70, UBQLN4, ANKZ
Protein Size: 358 -
Molecular Weight
- 40 kDa
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Gene ID
- 51726
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NCBI Accession
- NM_016306, NP_057390
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UniProt
- Q9UBS4
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Pathways
- ER-Nucleus Signaling
Target
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