DLL3 antibody (N-Term)

Catalog No. ABIN2782905

This anti-DLL3 antibody is a Rabbit Polyclonal antibody detecting DLL3 in WB. Suitable for Human, Mouse, Rat, Cow, Pig, Rabbit, Dog and Guinea Pig.

Quick Overview for DLL3 antibody (N-Term) (ABIN2782905)

Target: DLL3 (delta Like Protein 3 (DLL3))

Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLL3 Antibody

Binding Specificity: N-Term

Sequence: MVSPRMSGLL SQTVILALIF LPQTRPAGVF ELQIHSFGPG PGPGAPRSPC

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 85%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DLL3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DLL3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 618 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DLL3

Target: DLL3 (delta Like Protein 3 (DLL3))

Alternative Name: DLL3

Background: DLL3 is a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: SCDO1
Protein Size: 618

Molecular Weight: 54 kDa

Gene ID: 10683

NCBI Accession: NM_016941, NP_058637

UniProt: Q9NYJ7

Pathways: Notch Signaling