MAML3 antibody (Middle Region)
Quick Overview for MAML3 antibody (Middle Region) (ABIN2783063)
Target
See all MAML3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- YPVQQVNQFQ GSPQDIAAVR SQAALQSMRT SRLMAQNAGM MGIGPSQNPG
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Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against MAML3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MAML3
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 1133 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAML3 (Mastermind-Like 3 (MAML3))
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Alternative Name
- MAML3
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Background
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MAML3 acts as a transcriptional coactivator for NOTCH proteins. MAML3 has been shown to amplify NOTCH-induced transcription of HES1.
Alias Symbols: CAGH3, ERDA3, GDN, MAM-2, MAM2, TNRC3
Protein Interaction Partner: NOTCH1, ZZZ3, SCMH1, ZBTB1, RAI1, SUPT5H, NFX1, NOTCH3, NOTCH2, NOTCH4, MAML1, CSHL1,
Protein Size: 1133 -
Molecular Weight
- 122 kDa
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Gene ID
- 55534
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NCBI Accession
- NM_018717, NP_061187
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UniProt
- Q96JK9
Target
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