MAML3 antibody (Middle Region)

Catalog No. ABIN2783063

The Rabbit Polyclonal anti-MAML3 antibody (ABIN2783063) specifically detects MAML3 in WB. The antibody is reactive with Human, Mouse, Horse, Rabbit, Cow, Rat, Dog and Guinea Pig samples.

Quick Overview for MAML3 antibody (Middle Region) (ABIN2783063)

Target: MAML3 (Mastermind-Like 3 (MAML3))

Reactivity: Human, Mouse, Horse, Rabbit, Cow, Rat, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAML3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAML3 Antibody

Binding Specificity: Middle Region

Sequence: YPVQQVNQFQ GSPQDIAAVR SQAALQSMRT SRLMAQNAGM MGIGPSQNPG

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAML3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAML3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1133 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAML3

Target: MAML3 (Mastermind-Like 3 (MAML3))

Alternative Name: MAML3

Background: MAML3 acts as a transcriptional coactivator for NOTCH proteins. MAML3 has been shown to amplify NOTCH-induced transcription of HES1.
Alias Symbols: CAGH3, ERDA3, GDN, MAM-2, MAM2, TNRC3
Protein Interaction Partner: NOTCH1, ZZZ3, SCMH1, ZBTB1, RAI1, SUPT5H, NFX1, NOTCH3, NOTCH2, NOTCH4, MAML1, CSHL1,
Protein Size: 1133

Molecular Weight: 122 kDa

Gene ID: 55534

NCBI Accession: NM_018717, NP_061187

UniProt: Q96JK9