PHF5A antibody (Middle Region)

Catalog No. ABIN2783095

Product Details anti-PHF5A Antibody

Target: PHF5A (PHD Finger Protein 5A (PHF5A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF5A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ICGGPGVSDA YYCKECTIQE KDRDGCPKIV NLGSSKTDLF YERKKYGFKK

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PHF5A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PHF5A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 110 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHF5A

Target: PHF5A (PHD Finger Protein 5A (PHF5A))

Alternative Name: PHF5A (PHF5A Products)

Background: This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.
Alias Symbols: INI, MGC1346, SF3b14b, bK223H9.2, Rds3, SAP14b
Protein Interaction Partner: UBC, EZH2, BMI1, SUZ12, RNF2, SRPK3, FOXB1, PRPF31, SF3B5, RBM25, SF3B6, SF3B1, SF3B3, SF3B2, SF3B4, DDX23, SNRPB2, SNRPA1, SFPQ, S100A10, YBX1, NCL, HNRNPA1, DHX8, SF3A2, Sf3a1, SUMO2, RNU11, RNU12-2P,
Protein Size: 110

Molecular Weight: 12 kDa

Gene ID: 84844

NCBI Accession: NM_032758, NP_116147

UniProt: Q7RTV0