GSTM5 antibody (N-Term)

Catalog No. ABIN2783390

Product Details anti-GSTM5 Antibody

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MPMTLGYWDI RGLAHAIRLL LEYTDSSYVE KKYTLGDAPD YDRSQWLNEK

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GSTM5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSTM5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 218 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSTM5

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Alternative Name: GSTM5 (GSTM5 Products)

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.
Alias Symbols: GSTM5-5, GTM5
Protein Interaction Partner: AMOTL2, GSTM5, GSTM3, UBC, PPP1CC,
Protein Size: 218

Molecular Weight: 26 kDa

Gene ID: 2949

NCBI Accession: NM_000851, NP_000842

UniProt: P46439