GSTM5 antibody (N-Term)

Catalog No. ABIN656656

This Rabbit Polyclonal antibody specifically detects GSTM5 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for GSTM5 antibody (N-Term) (ABIN656656)

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM5 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32354

Product Details anti-GSTM5 Antibody

Binding Specificity: AA 14-43, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSTM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human GSTM5.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: GSTM5 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for GSTM5

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Alternative Name: GSTM5

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.

Molecular Weight: 25675

Gene ID: 2949

NCBI Accession: NP_000842

UniProt: P46439