Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) (C-Term) antibody

Catalog No. ABIN2783396

The Rabbit Polyclonal anti- antibody has been validated for WB. It is suitable to detect in samples from Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) (C-Term) antibody (ABIN2783396)

Target: Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6)

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Sequence: GERLVSDPAG EVGRVQDFLG LKRVVTDKHF YFNATKGFPC LKKAQGGSRP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against HS3ST6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HS3ST6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 311 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6)

Alternative Name: HS3ST6

Background: HS3ST6 is a single-pass type II membrane protein. It belongs to the sulfotransferase 1 family. It transfers a sulfuryl group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
Alias Symbols: HS3ST5
Protein Size: 311

Molecular Weight: 35 kDa

Gene ID: 64711

NCBI Accession: NM_001009606, NP_001009606

UniProt: Q96QI5

Pathways: Glycosaminoglycan Metabolic Process