Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) (C-Term) antibody

Catalog No. ABIN2783396

The Rabbit Polyclonal anti-Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 antibody is suitable to detect Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 in samples from Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) (C-Term) antibody (ABIN2783396)

Target: Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6)

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Sequence: GERLVSDPAG EVGRVQDFLG LKRVVTDKHF YFNATKGFPC LKKAQGGSRP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against HS3ST6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HS3ST6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 311 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6)

Alternative Name: HS3ST6

Background: HS3ST6 is a single-pass type II membrane protein. It belongs to the sulfotransferase 1 family. It transfers a sulfuryl group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
Alias Symbols: HS3ST5
Protein Size: 311

Molecular Weight: 35 kDa

Gene ID: 64711

NCBI Accession: NM_001009606, NP_001009606

UniProt: Q96QI5

Pathways: Glycosaminoglycan Metabolic Process