FNTA antibody (C-Term)

Catalog No. ABIN2783403

Product Details anti-FNTA Antibody

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Rabbit, Dog, Horse, Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNTA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DNKEDILNKA LELCEILAKE KDTIRKEYWR YIGRSLQSKH STENDSPTNV

Predicted Reactivity: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 100%, Rat: 92%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against FNTA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FNTA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 312 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FNTA

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Alternative Name: FNTA (FNTA Products)

Background: Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: FPTA, MGC99680, PGGT1A, PTAR2
Protein Interaction Partner: UBC, HK2, DYRK1A, RPL13A, SAFB2, TGM2, STAT2, INHBB, VAV2, HDAC6, PTP4A3, GBP1, CENPF, TGFBR1, TGFB1, KRAS, HRAS, RHOB, FNTB, ACVR1, PTP4A2,
Protein Size: 312

Molecular Weight: 36 kDa

Gene ID: 2339

NCBI Accession: NM_001018677, NP_001018197

UniProt: A6NJW0

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling