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GGPS1 antibody (C-Term)

This Rabbit Polyclonal antibody specifically detects GGPS1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Pig.
Catalog No. ABIN2783410

Quick Overview for GGPS1 antibody (C-Term) (ABIN2783410)

Target

See all GGPS1 Antibodies
GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

Reactivity

  • 71
  • 35
  • 15
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig

Host

  • 68
  • 6
Rabbit

Clonality

  • 70
  • 4
Polyclonal

Conjugate

  • 36
  • 7
  • 6
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GGPS1 antibody is un-conjugated

Application

  • 62
  • 32
  • 30
  • 9
  • 8
  • 6
  • 4
  • 4
  • 3
  • 2
Western Blotting (WB)
  • Binding Specificity

    • 15
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term

    Sequence

    LEDVGSFEYT RNTLKELEAK AYKQIDARGG NPELVALVKH LSKMFKEENE

    Predicted Reactivity

    Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%

    Characteristics

    This is a rabbit polyclonal antibody against GGPS1. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human GGPS1
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 300 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

    Alternative Name

    GGPS1

    Background

    GGPS1 is a member of the prenyltransferase family with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor.This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: GGPPS, GGPPS1
    Protein Interaction Partner: GGPS1, ATOX1, UBC,
    Protein Size: 300

    Molecular Weight

    35 kDa

    Gene ID

    9453

    NCBI Accession

    NM_001037277, NP_001032354

    UniProt

    O95749
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