SULT2B1 antibody (Middle Region)

Catalog No. ABIN2783445

Cited in 1 publication. The Rabbit Polyclonal anti-SULT2B1 antibody (ABIN2783445) specifically detects SULT2B1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse and Pig samples.

Quick Overview for SULT2B1 antibody (Middle Region) (ABIN2783445)

Target: SULT2B1 (Sulfotransferase Family, Cytosolic, 2B, Member 1 (SULT2B1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SULT2B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SULT2B1 Antibody

Binding Specificity: Middle Region

Sequence: YSKIAGQLKD PGTPDQFLRD FLKGEVQFGS WFDHIKGWLR MKGKDNFLFI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SULT2B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SULT2B1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 350 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SULT2B1 antibody (ABIN2783445)

Segala, de Medina, Iuliano, Zerbinati, Paillasse, Noguer, Dalenc, Payré, Jordan, Record, Silvente-Poirot, Poirot: "5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of tamoxifen in breast cancer cells." in: Biochemical pharmacology, Vol. 86, Issue 1, pp. 175-89, (2013) (PubMed).

Target Details for SULT2B1

Target: SULT2B1 (Sulfotransferase Family, Cytosolic, 2B, Member 1 (SULT2B1))

Alternative Name: SULT2B1

Background: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies.Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described.
Alias Symbols: HSST2
Protein Interaction Partner: ALS2CR12, SULT1B1, SULT2B1, SULT1A1, PRICKLE3, ACYP2, SULT1E1,
Protein Size: 350

Molecular Weight: 39 kDa

Gene ID: 6820

NCBI Accession: NM_004605, NP_004596

Pathways: Steroid Hormone Biosynthesis