STK3 antibody (C-Term)

Catalog No. ABIN2783469

This anti-STK3 antibody is a Rabbit Polyclonal antibody detecting STK3 in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Rabbit, Horse and Guinea Pig.

Quick Overview for STK3 antibody (C-Term) (ABIN2783469)

Target: STK3 (serine/threonine Kinase 3 (STK3))

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-STK3 Antibody

Binding Specificity: C-Term

Sequence: IEHNSTMLES DLGTMVINSE DEEEEDGTMK RNATSPQVQR PSFMDYFDKQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against STK3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human STK3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 491 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STK3

Target: STK3 (serine/threonine Kinase 3 (STK3))

Alternative Name: STK3

Background: Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand.Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758], Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-11 U26424.1 1-11 12-2826 BC010640.2 1-2815
Alias Symbols: FLJ90748, KRS1, MST2
Protein Interaction Partner: RASSF2, SLMAP, TRAF1, GAD1, FAM9B, RASSF4, GMCL1, TFPT, FBXW11, UBC, AURKB, RAE1, YWHAB, TSPYL1, STRN, STK4, PRKRIR, PLK1, RASSF5, SAV1, CTTNBP2NL, MOB1A, MAP1S, STRN3, STRN4, LATS2, FGFR1OP2, MOB4, RASSF1, ERLIN2, KIF2C, RASSF3, RUNDC3B, MOB1B, STRIP1, S
Protein Size: 491

Molecular Weight: 56 kDa

Gene ID: 6788

NCBI Accession: NM_006281, NP_006272

UniProt: Q13188

Pathways: Tube Formation