STK39 antibody (C-Term)
Quick Overview for STK39 antibody (C-Term) (ABIN2783491)
Target
See all STK39 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- CAVNLVLRLR NSRKELNDIR FEFTPGRDTA DGVSQELFSA GLVDGHDVVI
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Predicted Reactivity
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Characteristics
- This is a rabbit polyclonal antibody against STK39. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human STK39
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 545 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- STK39 (serine threonine Kinase 39 (STK39))
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Alternative Name
- STK39
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Background
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STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DCHT, DKFZp686K05124, PASK, SPAK
Protein Interaction Partner: UBC, FKBP9, EHD1, NOL3, API5, XPNPEP1, PCNA, NUBP1, SPP1, RELT, SLC12A6, SLC12A2, WNK4, SLC12A1, PRKCQ, MAPK14, MBP, STK39, HSPH1, AATK, OTOF, GSN,
Protein Size: 545 -
Molecular Weight
- 59 kDa
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Gene ID
- 27347
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NCBI Accession
- NM_013233, NP_037365
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UniProt
- Q9UEW8
Target
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