AASDHPPT antibody (C-Term)

Catalog No. ABIN2783499

Product Details anti-AASDHPPT Antibody

Target: AASDHPPT (Aminoadipate-Semialdehyde Dehydrogenase-phosphopantetheinyl Transferase (AASDHPPT))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Dog, Horse, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AASDHPPT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SRHQDVPSQD DSKPTQRQFT ILNFNDLMSS AVPMTPEDPS FWDCFCFTEE

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against AASDHPPT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AASDHPPT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 309 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AASDHPPT

Target: AASDHPPT (Aminoadipate-Semialdehyde Dehydrogenase-phosphopantetheinyl Transferase (AASDHPPT))

Alternative Name: AASDHPPT (AASDHPPT Products)

Background: AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
Alias Symbols: AASD-PPT, CGI-80, DKFZp566E2346, LYS2, LYS5
Protein Interaction Partner: USP22, UBC, TRAF2, SIAH1, ZC3HC1, EHD4, EHD1, TRIP13, NOL3, SGTA, PLCG1, HNRNPH1, CAPZA2, FBXO6, PAXIP1, BABAM1, MDFI,
Protein Size: 309

Molecular Weight: 36 kDa

Gene ID: 60496

NCBI Accession: NM_015423, NP_056238

UniProt: Q9NRN7