TRMU antibody (C-Term)

Catalog No. ABIN2783515

This Rabbit Polyclonal antibody specifically detects TRMU in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Rabbit, Rat, Guinea Pig and Horse.

Quick Overview for TRMU antibody (C-Term) (ABIN2783515)

Target: TRMU (tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase (TRMU))

Reactivity: Human, Mouse, Cow, Dog, Rabbit, Rat, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRMU Antibody

Binding Specificity: C-Term

Sequence: ALATGQFAVF YKGDECLGSG KILRLGPSAY TLQKGQRRAG MATESPSDSP

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRMU. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TRMU

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 421 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRMU

Target: TRMU (tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase (TRMU))

Alternative Name: TRMU

Background: TRMU is a member of the trmU family. It is a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.
Alias Symbols: MGC99627, MTO2, MTU1, TRMT, TRMT1, TRNT1
Protein Interaction Partner: UBC,
Protein Size: 421

Molecular Weight: 48 kDa

Gene ID: 55687

NCBI Accession: NM_018006, NP_060476

UniProt: O75648