CMAS antibody (N-Term)

Catalog No. ABIN2783528

The Rabbit Polyclonal anti-CMAS antibody has been validated for WB. It is suitable to detect CMAS in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio) and Horse.

Quick Overview for CMAS antibody (N-Term) (ABIN2783528)

Target: CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMAS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CMAS Antibody

Binding Specificity: N-Term

Sequence: GRGVEKPPHL AALILARGGS KGIPLKNIKH LAGVPLIGWV LRAALDSGAF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CMAS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CMAS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 434 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CMAS

Target: CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))

Alternative Name: CMAS

Background: CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.
Alias Symbols: CSS
Protein Interaction Partner: SUMO2, SUMO3, UBC, FBXO6, APP, SIGLEC12,
Protein Size: 434

Molecular Weight: 48 kDa

Gene ID: 55907

NCBI Accession: NM_018686, NP_061156

UniProt: Q8NFW8