PGS1 antibody (C-Term)

Catalog No. ABIN2783550

The Rabbit Polyclonal anti-PGS1 antibody has been validated for WB. It is suitable to detect PGS1 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit and Zebrafish (Danio rerio). There are 2+ publications available.

Quick Overview for PGS1 antibody (C-Term) (ABIN2783550)

Target: PGS1 (Phosphatidylglycerophosphate Synthase 1 (PGS1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PGS1 Antibody

Binding Specificity: C-Term

Sequence: RVQLQEYWRR GWTFHAKGLW LYLAGSSLPC LTLIGSPNFG YRSVHRDLEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PGS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PGS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 549 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PGS1 antibody (ABIN2783550)

Croston, Shepherd, Thapa, Nichols, Lewis, Dabkowski, Jagannathan, Baseler, Hollander: "Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart." in: Life sciences, Vol. 93, Issue 8, pp. 313-22, (2013) (PubMed).

Kiebish, Yang, Sims, Jenkins, Liu, Mancuso, Zhao, Guan, Abendschein, Han, Gross: "Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25086-97, (2012) (PubMed).

Target Details for PGS1

Target: PGS1 (Phosphatidylglycerophosphate Synthase 1 (PGS1))

Alternative Name: PGS1

Background: PGS1 functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
Alias Symbols: DKFZP762M186, MGC131960
Protein Interaction Partner: UBC, PDLIM1, GABARAP,
Protein Size: 549

Molecular Weight: 60 kDa

Gene ID: 9489

NCBI Accession: NM_024419

UniProt: Q32NB8