PGS1 antibody (AA 110-190)

Catalog No. ABIN7230612

The Rabbit Polyclonal anti-PGS1 antibody is suitable to detect PGS1 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for PGS1 antibody (AA 110-190) (ABIN7230612)

Target: PGS1 (Phosphatidylglycerophosphate Synthase 1 (PGS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PGS1 Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-PGS1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PGS1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PGS1 protein at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PGS1

Target: PGS1 (Phosphatidylglycerophosphate Synthase 1 (PGS1))

Alternative Name: PGS1

Background: Biglycan, Bone/cartilage proteoglycan I, PG-S1BGN encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. BGN and the related gene decorin are thought to be the result of a gene duplication.

Molecular Weight: 40kD

Gene ID: 633

UniProt: P21810