QTRT1 antibody (Middle Region)

Catalog No. ABIN2783576

This Rabbit Polyclonal antibody specifically detects QTRT1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig and Goat.

Quick Overview for QTRT1 antibody (Middle Region) (ABIN2783576)

Target: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QTRT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-QTRT1 Antibody

Binding Specificity: Middle Region

Sequence: KDKPRYLMGV GYATDLVVCV ALGCDMFDCV FPTRTARFGS ALVPTGNLQL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against QTRT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human QTRT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 403 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for QTRT1

Target: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Alternative Name: QTRT1

Background: This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X.
Alias Symbols: FP3235, TGT, TGUT
Protein Interaction Partner: UBC, NEDD8, UBD, COPS6, NDUFA4L2, ZBTB16, SETDB1, UNC119, SH3GL3,
Protein Size: 403

Molecular Weight: 44 kDa

Gene ID: 81890

NCBI Accession: NM_031209, NP_112486

UniProt: Q80VS3

Pathways: Ribonucleoside Biosynthetic Process