GSTZ1 antibody (N-Term)
Quick Overview for GSTZ1 antibody (N-Term) (ABIN2783617)
Target
See all GSTZ1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against GSTZ1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human GSTZ1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 216 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))
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Alternative Name
- GSTZ1
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Background
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GSTZ1 is a member of the glutathione S-transferase (GSTs) super-family which are important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia.This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.
Alias Symbols: GSTZ1-1, MAAI, MAI, MGC2029
Protein Interaction Partner: GSTZ1, UBC, BAG3, PPP1CC, GSS, HNRNPL,
Protein Size: 216 -
Molecular Weight
- 24 kDa
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Gene ID
- 2954
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NCBI Accession
- NM_145870, NP_665877
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UniProt
- O43708
Target
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