CHSY3 antibody (N-Term)

Catalog No. ABIN2783650

This Rabbit Polyclonal antibody specifically detects CHSY3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit.

Quick Overview for CHSY3 antibody (N-Term) (ABIN2783650)

Target: CHSY3 (Chondroitin Sulfate Synthase 3 (CHSY3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHSY3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHSY3 Antibody

Binding Specificity: N-Term

Sequence: PPLQQRRRGR EPEGATGLPG APAAEGEPEE EDGGAAGQRR DGRPGSSHNG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CHSY-2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHSY-2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 882 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHSY3

Target: CHSY3 (Chondroitin Sulfate Synthase 3 (CHSY3))

Alternative Name: CHSY-2

Background: CHSY-2 has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. CHSY-2 transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity of CHSY-2 is much reduced compared to CHSY1.CSS3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities (Yada et al., 2003 [PubMed 12907687]).[supplied by OMIM].
Alias Symbols: CHSY2, CSS3, CHSY-2
Protein Size: 882

Molecular Weight: 100 kDa

Gene ID: 337876

NCBI Accession: NM_175856, NP_787052

UniProt: Q70JA7

Pathways: Glycosaminoglycan Metabolic Process