TMEM135 antibody (N-Term)

Catalog No. ABIN2783894

This Rabbit Polyclonal antibody specifically detects TMEM135 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit and has been mentioned in 2+ publications.

Quick Overview for TMEM135 antibody (N-Term) (ABIN2783894)

Target: TMEM135 (Transmembrane Protein 135 (TMEM135))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM135 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TMEM135 Antibody

Binding Specificity: N-Term

Sequence: SLKIYAPLYL IAAILRKRKL DYYLHKLLPE ILQSASFLTA NGALYMAFFC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TMEM135. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TMEM135

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 458 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TMEM135 antibody (ABIN2783894)

Lee, Higuchi, Ikeda, Macke, Takimoto, Pattnaik, Liu, Chu, Siepka, Krentz, Rubinstein, Kalejta, Thomson, Mullins, Takahashi, Pinto, Ikeda: "Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies." in: eLife, Vol. 5, (2016) (PubMed).

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Target Details for TMEM135

Target: TMEM135 (Transmembrane Protein 135 (TMEM135))

Alternative Name: TMEM135

Background: The exact function of TMEM135 remains unknown.
Alias Symbols: DKFZp686I1974, FLJ22104, PMP52
Protein Interaction Partner: UBC,
Protein Size: 458

Molecular Weight: 52 kDa

Gene ID: 65084

NCBI Accession: NM_022918, NP_075069

UniProt: Q86UB9