Plexin A2 antibody (N-Term)
Quick Overview for Plexin A2 antibody (N-Term) (ABIN2783972)
Target
See all Plexin A2 (Plxna2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- SVASYVYNGY SVVFVGTKSG KLKKIRADGP PHGGVQYEMV SVLKDGSPIL
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Predicted Reactivity
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Characteristics
- This is a rabbit polyclonal antibody against PLXNA2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PLXNA2
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 1894 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios." in: Schizophrenia research, Vol. 99, Issue 1-3, pp. 365-6, (2008) (PubMed).
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: "No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios." in: Schizophrenia research, Vol. 99, Issue 1-3, pp. 365-6, (2008) (PubMed).
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- Plexin A2 (Plxna2)
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Alternative Name
- PLXNA2
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Background
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PLXNA2 is a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.
Alias Symbols: FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2
Protein Interaction Partner: CEMIP, FNBP4, UBAP2L, IFT80, HACE1, DHX37,
Protein Size: 1894 -
Molecular Weight
- 211 kDa
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Gene ID
- 5362
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NCBI Accession
- NM_025179, NP_079455
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UniProt
- O75051
Target
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