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Plexin A2 antibody (N-Term)

The Rabbit Polyclonal anti-Plexin A2 antibody has been validated for WB. It is suitable to detect Plexin A2 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). There is 1 publication available.
Catalog No. ABIN2783972

Quick Overview for Plexin A2 antibody (N-Term) (ABIN2783972)

Target

See all Plexin A2 (Plxna2) Antibodies
Plexin A2 (Plxna2)

Reactivity

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  • 15
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Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Plexin A2 antibody is un-conjugated

Application

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Western Blotting (WB)
  • Binding Specificity

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    N-Term

    Sequence

    SVASYVYNGY SVVFVGTKSG KLKKIRADGP PHGGVQYEMV SVLKDGSPIL

    Predicted Reactivity

    Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    Characteristics

    This is a rabbit polyclonal antibody against PLXNA2. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human PLXNA2
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 1894 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Budel, Shim, Feng, Zhao, Hisama, Strittmatter: "No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios." in: Schizophrenia research, Vol. 99, Issue 1-3, pp. 365-6, (2008) (PubMed).

  • Target

    Plexin A2 (Plxna2)

    Alternative Name

    PLXNA2

    Background

    PLXNA2 is a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.
    Alias Symbols: FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2
    Protein Interaction Partner: CEMIP, FNBP4, UBAP2L, IFT80, HACE1, DHX37,
    Protein Size: 1894

    Molecular Weight

    211 kDa

    Gene ID

    5362

    NCBI Accession

    NM_025179, NP_079455

    UniProt

    O75051
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