BRI3BP antibody (C-Term)

Catalog No. ABIN2784121

Product Details anti-BRI3BP Antibody

Target: BRI3BP (BRI3 Binding Protein (BRI3BP))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Guinea Pig, Horse, Rat, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRI3BP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GFYWRSSPSG PSNPSNPSVE EKLEHLEKQV RLLNIRLNRV LESLDRSKDK

Predicted Reactivity: Cow: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against BRI3BP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BRI3BP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 251 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRI3BP

Target: BRI3BP (BRI3 Binding Protein (BRI3BP))

Alternative Name: BRI3BP (BRI3BP Products)

Background: BRI3BP is involved in the structural dynamics of the ER and affects mitochondrial viability.It is widely expressed in animal cell types, that seems to possess a pro-apoptotic property and can potentiate drug-induced apoptosis.The protein is highly expressed in brain, kidney, and liver, and it mapped to human chromosome 12q24.2-qter.Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA45, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-131 AM055744.1 1-131
Alias Symbols: BNAS1, HCCR-2, KG19, HCCR-1, HCCRBP-1
Protein Interaction Partner: RNF2, ESR1, UBC,
Protein Size: 251

Molecular Weight: 28 kDa

Gene ID: 140707

NCBI Accession: NM_080626, NP_542193

UniProt: Q8WY22