BRI3BP antibody (C-Term)

Catalog No. ABIN2784121

This Rabbit Polyclonal antibody specifically detects BRI3BP in WB. It exhibits reactivity toward Human, Mouse, Guinea Pig, Horse, Rat, Cow and Rabbit.

Quick Overview for BRI3BP antibody (C-Term) (ABIN2784121)

Target: BRI3BP (BRI3 Binding Protein (BRI3BP))

Reactivity: Human, Mouse, Guinea Pig, Horse, Rat, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRI3BP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BRI3BP Antibody

Binding Specificity: C-Term

Sequence: GFYWRSSPSG PSNPSNPSVE EKLEHLEKQV RLLNIRLNRV LESLDRSKDK

Predicted Reactivity: Cow: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against BRI3BP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BRI3BP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 251 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRI3BP

Target: BRI3BP (BRI3 Binding Protein (BRI3BP))

Alternative Name: BRI3BP

Background: BRI3BP is involved in the structural dynamics of the ER and affects mitochondrial viability.It is widely expressed in animal cell types, that seems to possess a pro-apoptotic property and can potentiate drug-induced apoptosis.The protein is highly expressed in brain, kidney, and liver, and it mapped to human chromosome 12q24.2-qter.Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA45, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-131 AM055744.1 1-131
Alias Symbols: BNAS1, HCCR-2, KG19, HCCR-1, HCCRBP-1
Protein Interaction Partner: RNF2, ESR1, UBC,
Protein Size: 251

Molecular Weight: 28 kDa

Gene ID: 140707

NCBI Accession: NM_080626, NP_542193

UniProt: Q8WY22